Sentence examples for combination variant from inspiring English sources
Interestingly, another combination variant (4C6: R149I/showedS215D) showed not only lowered binding to DR5, but also decreased binding affinity to both decoy receptors in solution (Supplementary Figure S2).
Counts are stratified by each combination of two variants; for each combination, variant 1 (v1) is the variant in the gene listed first and (v2) is the variant in the gene listed second; The total counts for LOAD patients and controls are given underneath the stratified counts.
Two combination variants showing the highest affinity increase to DR4 and affinity decrease for DR5 were selected for further studies.
Mutation S159R was incorporated in all the combination variants, showing a high affinity ratio change (Supplementary Table 1).
The characteristics of these single mutants were used for rational design of nine combination variants, containing between two and six mutations each.
Comparison between single variants and combination variants in BJAB cell lines showed that 4C7 displays a greatly improved capability to induce cell death when compared with rhTRAILWT, to the single variants and to a combination of three mutations (Supplementary Figure S3).
Thus, it is possible that S versus LEW is not the only strain combination with variants of Adamts16 representing candidates for the quantitative trait of BP.
Therefore, a combination of variant channel conditions together with these kind of traffic patterns could cause a performance degradation since the OLLA may not be able to update its offset fast enough to follow the channel variations.
In a practical application, one will most likely rely on a combination of variant callers to avoid the biases of a single method.
Statistically, epistasis refers to interaction between variants at multiple loci in which the total effect of the combination of variants at the different loci may differ considerably from a linear combination of the effects of individual loci.
