Sentence examples for combination trials from inspiring English sources

In the clinical setting, the majority of PARP inhibitor combination trials have focused upon combining PARP inhibitors with standard of care therapies [reviewed in (Lord & Ashworth, 2012)].

In 2017 alone, 469 new combination trials were started with a combined target enrollment of 52,539 patients.

The potential of presurgical treatment was illustrated by comparing results from the IMPACT (Immediate Preoperative Anastrozole Tamoxifen or Combined with Tamoxifen) and ATAC (Arimidex, Tamoxifen Alone or Combination) trials.

Nationwide, hundreds of combination trials are underway.

The pairing still makes up the lion's share of immunotherapy combination trials.

Other combination trials are targeting different mechanisms of T-cell suppression that tumours use to fend off the immune system.

Mitomycin C (MMC), which shows some bioreductive activation in vitro, has been tested in combination trials.

The hundreds of combination trials that are starting each year will soon deliver an avalanche of data that should yield insight on how best to harness anticancer immunity in each person.

The particular challenge of how to design combination trials is addressed, with focus on the potential of new adaptive and model-based designs.

In this paper, we present the dfcomb R package for the implementation of a single prospective clinical trial or simulation studies of phase I combination trials in oncology.

These data suggest that vitamin D holds a key role for the effector functions of MAMs and that vitamin D supplementation in IMiD combination trials could further increase the therapeutic efficacy of anti-CD38 antibodies such as MOR202, which remains to be investigated in clinical studies.