Sentence examples for combination to target from inspiring English sources
Understanding downstream RAS-effectors that mediate oncogenesis in a RAS mutant setting will help tailor treatments that use RAS-effector inhibitors either alone or in combination to target RAS-driven tumors.
Therapy involves both identification of the fault and a suitable drug combination to target the fault.
Together, these transducers can be used in combination to target the dermis (1.5 mm), deep dermis (3.0 mm), or the subdermal tissues (4.5 mm) including the SMAS layer.
The intensity of treatment was categorized by numbers of agents used in combination to target elevated BP, and to lower blood glucose.
These investigations clearly demonstrate a synergistic action when both BsAb are used in combination to target saporin against CD7 and CD38 expressed on the surface of the HSB-2 cell line.
Furthermore, the prohibitive costs and challenges imposed by both industry and regulators for combining targeted therapeutics may mitigate against the development of rational drug combinations to target intra-tumoural heterogeneity to limit the acquisition of drug resistance.
It is quite possible to develop combinations to target all the 28 proteins based on our docking results.
Future studies may be warranted to capitalize on using these combinations to target multiple oncogenic pathways to enhance efficacy and lower potential off-target effects.
Depending on the mechanisms of resistance, patients with relapsed diseases may further benefit from (1) new generation of targeted agents designed to address the resistance mechanisms; and (2) combination therapy to target multiple pathways simultaneously including resistance mechanisms.
Fortasyn Connect (FC) is a specific nutrient combination designed to target synaptic dysfunction in Alzheimer's disease by providing neuronal membrane precursors and other supportive nutrients.
For example, combination therapies to target both oncogenic and TSG mutations may benefit patients within a relevant molecularly defined segment.
