The deal is one of the largest cross-border European banking combinations to date, and Credit Commercial is the first large French retail bank to fall into foreign control.
3 4 Many of these features have been demonstrated in small studies, in differing combinations to date.
Clinical experience with radiotherapy-vaccine combinations to date is extremely limited.
The results obtained with triple-drug combinations to date do not allow definitive conclusions to be drawn with respect to the overall clinical benefit of the addition of a third drug to dual-agent chemotherapy.
The recent comparison of efficacy between etanercept and etanercept in combination with methotrexate by Gottlieb et al. [ 57] is one of the most robust combination trials to date in patients with moderate-to-severe psoriasis.
Another FDA panel endorsed Gilead's new Quad pill, which is the simplest, most effective combination drug to date.If the process for developing HIV drugs has been unusual, selling them has been even more so.
We found no evidence of consistent up- or down-regulation in liver, kidney, or testes using any gene set combination reported to date, including the set of bound genes by E2f4 in mouse.
The most successful novel combination up to date corresponds to AS formulations.
Most combination studies to date have used VPA, which requires higher concentrations than newer HDAC inhibitors but is relatively selective for class-I-HDACs and leads to degradation of HDAC 2 (Göttlicher et al. 2001).
The phenotypic similarity of all eak single mutants and the observation that no eak;eak double mutant combination tested to date exhibits phenotypic enhancement compared to eak single mutants indicate that the EAK proteins are components of a single pathway.
