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Although well studied in vitro over 10 years ago, aztreonam combination testing has been poorly documented with newer or commonly used agents against contemporary isolates.
Etest methodology was used to facilitate minimum inhibitory concentration (MIC) and antimicrobial combination testing on 258 isolates of Bcc, identified to species level by matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry (MALDI-TOF/MS).
Josh Langhoff of PopMatters gave the box set a score of 10 out of 10 and felt that the set is "about sound: the tangible, physically beautiful sounds of Smith's imperative trumpet and of different instruments in combination, testing their own limits".
An additional caution is then that combination testing data could not reliably be applied to all members of a clonal group.
In-vitro combination testing of antimicrobial combinations using clinically relevant drug concentrations instead of MIC-based concentrations is recommended to guide clinicians in determining which antimicrobial combination and at what doses are to be used as empiric therapy.
Although this method cannot make the results available to the clinicians in a timely manner for individual bedside decisions, it can help narrow down the possible alternative combinations to use for empiric treatment while waiting for the combination testing to be conducted for every CR AB infection.
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We then use Fisher's combination test to combine position-by-position probabilities among experiments.
Both p-values will be combined using the Fisher's combination test.
Moreover, the combination test revealed a stronger effect of the MMP1-MMP3.1 2G/2G-6A/6A combined genotype.
"My understanding is that this is a combination test and launch," Mr. Pearlstine said.
Description: Combination test for IgG and IgM, The combination of the two tests distinguishes antibodies induced by acute viral infection and/or vaccination.
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