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We then use Fisher's combination test to combine position-by-position probabilities among experiments.
Association between MMP genotypes and colorectal adenomas was first tested for each polymorphism separately and then for combined genotypes using the combination test.
This finding underlines the importance of using the combination test for demonstrating combined effects of polymorphisms with little or no individual effect.
Both p-values will be combined using the Fisher's combination test.
14 The Fisher combination test was introduced to combine evidence from different subgroups and make inferences 14 as follows.
Given the independence of our data sets, we chose to address the problem of combining multiple testing results by using Fisher's combination test.
The (first) amendment should specify the combination test to be applied in order to combine the different phases.
Moreover, the combination test revealed a stronger effect of the MMP1-MMP3.1 2G/2G-6A/6A combined genotype.
In a hybrid design, we only want to determine whether the combined evidence reaches the prespecified significance level, using the Fisher combination test.
One approach subdivides the study into several (two or more) stages and combines the p-values of the different stages using Fisher's combination test.
"My understanding is that this is a combination test and launch," Mr. Pearlstine said.
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