Sentence examples for combination study with from inspiring English sources
Mice were given weekly injections following the same protocol used in the combination study, with the exception of allopregnanolone/corn oil (total of three injections given at P7, P14, and P21).
SAR650984 is currently being tested in a phase I dose-escalation study and a phase Ib combination study with lenalidomide and dexamethasone [ 183, 184].
To investigate whether DNA repair processes play a role in the enhancement of TH-302 cytotoxicity by Chk1 inhibitors, we conducted an in vitro combination study with TH-302 and AZD7762 using paired HDR-proficient and HDR-deficient cells.
With respect to safety and tolerability, the present analysis demonstrated that saxagliptin was generally well tolerated in older patients; the overall incidence of AEs was similar in the older and younger subgroups in the pooled analysis and also in the initial combination study, with no notable differences between the subgroups and the overall populations of the individual studies.
The purpose of this study was to investigate the utility of plasma pharmacokinetic and pharmacodynamic measures including plasma deoxynucleosides, homocysteine and methylmalonic acid concentrations in understanding the time course and extent of the inhibition of thymidylate synthase (TS) by pemetrexed in the context of a phase I/II combination study with vinorelbine.
Two additional unpublished studies of memantine in mild to moderate AD, a monotherapy study conducted in Europe and a combination study with a ChEI conducted in the US, failed to show statistically significant benefits over placebo in the primary outcome measures.
The combination studies with advanced oxidation process involve the advanced Fenton process and combination of ultrasound with UV based oxidation.
The hope remains that small molecule inhibitors can provide a complementary approach to mAb therapeutics in terms of efficacy and dosing flexibility, particularly in combination studies with cytotoxics and epidermal growth factor receptor (EGFR) antagonists.
Combination studies with agents such as abiraterone, enzalutamide, and docetaxel can be considered in the future.
In vitro and in vivo combination studies with the tyrosine inhibitor semaxinib were also performed.
Combination studies with metformin realize a hemoglobin A1c reduction of 0.65%–1.1%.
