Although such tight glycemic control may not be feasible, the study of P. Kopecký et al., in this issue, suggests that a combination approach of two methodologies such as enhanced model predictive control algorithm and continuous glucose monitoring would be more reliable and accurate.
In this paper it is made a comparison between the classical experimental design and one of these direct search methods, developed by Nelder and Mead (1965), known as the Nelder Mead simplex (NMS), trying to overcome the disadvantages and maximize the advantages of both approaches, trough a proposed combination of the two methodologies.
The synergistic combination of the two methodologies to address the design and assessment of treatment facilities can serve to identify the most sustainable options, embracing simultaneously a wide variety of analysis criteria, and enhancing the calculation of environmental savings.
The combination of those two methodologies - molecular dynamics with the use of physics-base UNRES force field and the kink approach have been applied to study the flexibility and movement of the kinks as well as their formation and disappearance in the folding process.
Our results, however, not only show that there are some discrepancies between transcriptome and the proteome data, but also indicate that the combination of the two methodologies can potentially lead to a more complete understanding of the molecular biology of S. cerevisiae.
This paper discusses how the combination of the two methodologies has been used to identify ingredient levels and/or processing conditions that most affect product texture variability (product texture in this case being a temporal phenomenon).
Therefore a judicious approach might be to use a combination of the two methodologies, as demonstrated here for the fgf24 EGFP BAC and in an earlier study [ 38].
This paper reports on the design, implementation and assessment of a new approach course structure based on the combination of three cooperative methodologies.
The complex combination of at least two methodologies being created for a very special problem makes transferability difficult [80].
The applied methodology can be seen as an alternating combination of two established approaches: qualitative expert interviews [38] and expert validations.
