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Our data demonstrate that MASS-1 measures reliable binding kinetic parameters and has an appropriate combination of throughput and sensitivity to support discovery and development of therapeutic antibodies.
This combination of throughput and sensitivity enables the detection of rare transcripts from nanograms of RNA.
The 454 Titanium sequencing platform offers an ideal combination of throughput and long read length to enable de novo sequence assembly of whole genomes.
Illumina sequence reads were generated, as the Illumina platforms are currently the most commonly used high-throughput platforms [ 56], and their combination of throughput and read length are well-suited to aDNA sequencing [ 57].
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At this stage, the combination of low-throughput and high-throughput datasets curated by databases such as BioGrid (see above) indicate that the community has assembled about 20% of that number of high quality interactions of the Reference interactome network.
However, a combination of high throughput sequencing, more revealing experimental designs, and phylogenetic community analyses provide insights into mechanisms that shape early microbial communities.
The combination of high throughput capabilities of Mass Spectrometry, together with increased specificity and sensitivity that can be compared to immunoassays in some cases are the main advantages that make MS based applications very popular for quantitative validation studies [110].
Due to its unique combination of sample throughput, measurement precision, temporal sampling and experimental versality, HDD provides a novel biomechanics-based experimental platform for quantifying the effects of proteins (cytokines, growth factors, enzymes, antibodies) or small molecules on the degradation of soft tissues or tissue engineering constructs.
A combination of high throughput technologies and bioinformatics analysis provides important means in generating a testable hypothesis for mechanistic study.
Taken together, in this study using a combination of high throughput mass spectrometry and statistical validation methods, we provide the first evidence of metabolic reprogramming between AS/AR matched pair isolates.
The combination of high throughput screenings, phenotypic analyses and localization studies provides new insight into the function of Ccw12p.
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