Evidence suggested that a combination of cold, starvation and disease including scurvy, pneumonia and tuberculosis, all made worse by lead poisoning, killed everyone in the Franklin party.
At a distance of 150 miles from their base camp and 11 miles from the next depot, Scott and his companions died from a combination of exhaustion, starvation and extreme cold.
The combination of serum starvation and CDDP further decreased clonogenicity in the p53-proficient cells, but not in p53-deficient cells.
When renal epithelial cells are exposed to agents that produce necrosis and apoptosis investigators report a decrease in TER along with a subsequent increase in paracellular flux [ 27, 35], we confirmed this finding in the MDCK system by using a combination of energy starvation and ATP depletion.
It is concluded that the weight loss produced by TNF arises from a combination of semi-starvation and a reduced water intake, and that the effect only occurred with the first administration of TNF.
As the infections were accompanied by cachexia in all birds the ultimate cause of death might have been a combination of lesions and starvation; although it is not clear whether initial starvation led to increased vulnerability to infections or vice versa.
