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For each combination of prevalence of the prognostic factor and magnitude of the interaction ran 10 trials to obtain 10 interim test statistics for each combination of parameters.
Indeed, multiple genetic risk distributions can correspond to a given combination of prevalence and heritability; each such distribution, however, can lend itself differently to genetic prediction.
35 The observed prevalence from the NPR is measured using a combination of prevalence and incidence, since it includes patients with either a newly diagnosed cancer or a diagnosis in the past in continuous need of treatment.
Many Japanese studies on more or less selected populations of IIP patients reported a frequency of lung cancer that was mostly a combination of prevalence and incidence, making them difficult to interpret.
The problem is known from diagnostic testing, where a trade-off between sensitivity and specificity is made, e.g., by taking their sum (equivalent to the Youden index) or a weighted sum with a combination of prevalence and utilities as weights.
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Since there were 10 different combinations of prevalence of the prognostic factor and magnitude of the interaction effect and 10 trials for each combination, the plot generated 100 points.
Firstly, although the overall sample size was large (n = 617), the combination of the prevalence of headache type and other factors with low prevalence such as depression resulted in small case sizes for those factors.
BW injuries were frequent due to the combination of high prevalence of BWs and of home stairs.
The combination of this prevalence effect with the effects of mixing specific and categorical targets produces dramatic differences in error rates in the critical case of rare, categorical targets.
If sustained, the combination of high prevalence and low survival among infected individuals portend adversity for a mule deer population.
The dramatic decrease in stomach cancer death rates that has occurred in most economically developed or transitioning countries is thought to result from the combination of reduced prevalence of Helicobacter Pylori infection and the benefits of refrigeration [24], [25].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com