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► Future improvements are likely to require a combination of methodological advancements and expanded basic data.
These questions address key domains (eg. comprehensive search, validity assessment, results combination) of methodological quality.
The discordant results are probably based on a combination of methodological causes and content-related reasons.
However, we envision that a combination of methodological curatorial approaches and software tools will continue to be required for the range of different tasks involved in these types of efforts.
Through a combination of methodological approaches, including high resolution immunogold cytochemistry (Amiry-Moghaddam and Ottersen 2013), we could show that the different members of this complex exhibit distinct ontogenetic profiles.
Through a combination of methodological approaches, including light microscopic and high resolution immunogold cytochemistry, quantitative RT-PCR, and Western blotting, we demonstrate that the different members of this complex exhibit distinct ontogenic profiles––with the extracellular matrix (ECM) proteins laminin and agrin appearing earlier than the other members of the complex.
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Different combinations of methodological choices and modeling assumptions produce widely varying results, particularly at regional scales, and can produce fundamentally different conclusions about the overall impact of climate change on O3-related health effects.
Results: Different combinations of methodological choices produced a range of estimates of national O3-related mortality from roughly 600 deaths avoided as a result of climate change to 2,500 deaths attributable to climate change (although the large majority produced increases in mortality).
Seven of the reviewed papers were methodological papers or a combination of a methodological paper applied in a specific case [31, 44, 50, 58, 78, 87, 108], while the remaining articles were primarily case studies.
The combination of different methodological approaches within the project allows us to produce a robust evaluation of future EGS provision in mountain regions under global change, taking interactions between the ecological, socio-economic and policy domains into account (Huber et al. 2013b).
The present study therefore examines age-related alterations in automatic semantic retrieval and memory structure with a novel combination of critical methodological factors, i.e., the selection of subjects, a well-designed paradigm, and electrophysiological methods that result in unambiguous signal markers.
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