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The combination of genotypes in these interactive SNPs can help to pin-point individuals with greater asthma risk (Figure 3).
To find out the risk associated with each high-intrinsic set, we categorized the individuals on the basis of combination of genotypes that defined the set.
These experiments, however, require the identification of single feature polymorphisms (SFP) between the cross parents for each new combination of genotypes, which raises the cost of experiments.
For fitness measurements in the first experiment, the 20 best-matched pairs (of an initial 28) were chosen from each combination of genotypes.
Let λi denote the relative risk of the disease for a particular combination of genotypes (gi) and p denote the average lifetime risk.
When in these patients, a combination of genotypes at different risk loci – all of which part of different pathways – is present (cfr as in the SNP classification tree), the patient will end up developing a specific disease subphenotype, independent from the development of CD overall.
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Rice growth is influenced by a combination of genotype, environment and management factors.
The quite recently established eukaryotic molecular biology tool, the baculovirus display vector system (BDVS), allows combination of genotype with phenotype and thereby enables presentation of eukaryotic proteins on the viral envelope or capsid.
We have fine-mapped 64 known PrCa regions through a combination of genotyping and imputation.
However, combination of genotype and resistance heterogeneity is a diagnostic and therapeutic challenge (8 ).
For each combination of genotype (Wt versus Tyk2-/) and treatment (control versus LPS) we carried out three independent replicate experiments.
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