Sentence examples for combination of alterations from inspiring English sources

This combination of alterations results in a markedly altered current profile under AP voltage clamp (Fig. 5).

During acute hypoxia a combination of alterations usually associated with reduced IGF action was observed.

However, classic genetic CaP engineering in mouse makes this a daunting task because generation, breeding based combination of alterations and non-invasive monitoring of disease are too time consuming and costly.

Combination of mutations in the same protein results in combination of alterations provided by single mutation.

This difference presumably reflects a combination of alterations in facial shape, growth, morphogenesis and gene expression between these species.

In addition to the lymphocyte specific transcriptional pattern induced by both types of DNA damage, genotoxic damage induces a potentially oncogenic combination of alterations of genes and biological response pathways.

GISTIC differs from these methods in that it assesses the statistical significance of the combination of alteration frequency and magnitude across the genome.

This is attributable to a combination of alteration of the electrical properties of intercellular gap junctions; structural remodelling of the myocardium; and generation of EADs/DADs that per se have slower conduction.

Logic-based modeling uncovers combinations of alterations that sensitize to drugs, while machine learning demonstrates the relative importance of different data types in predicting drug response.

For successful inhibition, detailed molecular information on individual tumours will be required and it is already clear that different tumour types show distinct combinations of alterations.

In this study, we aimed to investigate how combinations of alterations in important genes of the PI3K and MAPK pathways correlate with different non-small cell lung cancer (NSCLC) tumor subtypes.