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Thus, pharmacological approaches that can achieve a favorable combination of a reduced microglia-mediated neuro-inflammation, and an enhanced Aβ clearance may be beneficial for preventing the progression of the disease.
Based on current evidence, weight-loss strategies that include a combination of a reduced calorie intake diet and increased physical activity appear to be most effective [ 3, 4].
At the level of a single neuron, CSD is characterized by a depolarization to nearly zero membrane potential, which is achieved by the combination of a reduced electrochemical gradient for potassium and the opening of persistent sodium and potassium conductances (Somjen, 2004).
It is generally believed however that a 1D structure (through a combination of a reduced recombination (achieving high electron-transfer rate) process and lower surface area) would have reduced solar-to-electrical conversion efficiencies [13].
Using an exhaustive search of the best combination of a reduced set of 14 biomarkers, the minimum number required for classification of breast tumours into the six classes was reduced from 25 biomarkers to 10.
This combination of a reduced military but continued conflict gave rise to an unprecedented new industry of private military firms.
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The combination of a reducing end-specific exoglucanase (GH48) and a non-reducing end-specific processive endoglucanase (GH9-CBM3c) connected by Family 3b CBMs is most likely responsible for this unique mechanism.
In summary, ALP-treated sections showed a combination of effects: a reduced DAPI-polyP∶DAPI-DNA ratio (520∶430 nm), a peak position shift to lower wavelengths, and a reduction in the FWHM, consistent with the reduction in DAPI-polyP emission.
In both situations, knowledge of the particulate and/or gaseous fire signatures as they occur under the unique combination of a reduced-gravity environment and materials typical of spaceflight applications is essential for the design of spacecraft fire detectors and habitat sensors.
The observed reduction in reproductive success of intersex fish could have resulted from a combination of factors, including a reduced ability to release milt due to blocked or obstructed sperm ducts, reduced sperm quality, reduced hatching success or survival of fry, and/or reduced ability to compete with other males or attract females.
Hydrogel biocomposites were prepared from a combination of thermally reduced graphene oxide (rGO) and natural and synthetic polymers followed by encapsulation of antimalarials.
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