Thus, there is a large difference between the actual and expected frequency of AAG-AAG in YEF3 (0.014367 – 0.001468 = 0.01289), indicating that the AAG AAG codon combination is over-represented in this gene.
For prevalences typical of antenatal practices (30%) and STD clinics (40 50%), the PPV of the test combination was over 97% and 98%, respectively.
Upon analysis, the 256 genes (Supplementary Table S4) with limited two-codon combination diversity (less than or equal to 100 different combinations) were over-represented in the theme of translation (19) (P ≤ 0.05).
Furthermore, the enhanced cell proliferation inhibition by MTE → MTE + gefitinib sequential combination was over each agent alone.
The Inr_MTE combination is also over-represented at a distance of 16 bp (not only 17 bp), although experiments showed synergism only at 17 bp [ 2].
Controlling diseases such as transthyretin amyloidosis would presumably require multiple treatments over several years, so researchers also need to find out if the siRNA and lipid nanoparticle combination is safe over the long term, Kay says.
As a visual concept often exhibits great appearance variance, a canonical MKL approach may not generate satisfactory results when a uniform kernel combination is applied over the input space.
There is no evidence suggesting that this combination is advantageous over gemcitabine or 5-FU alone in the treatment of advanced pancreatic cancer.
Moreover, a synthetic DMARD combination is preferred over DMARD monotherapy as there is increasing evidence of a window of opportunity in patients with early RA in which the antirheumatic therapy should be as intense as possible, also indicating a need for early identification of these patients.
This new GMRES/preconditioner combination is shown to be over an order of magnitude more efficient than the previous wave-number independent preconditioner for problems with large numbers of time instances and/or large reduced frequencies.
Statistical significance of such an (M,G,W) combination means that motif M is over-represented in window W on the promoters of the genes that belong to the human functional GO group G.
