However, if we follow the recommendations [38], we treat groups of patients with very low risks of recurrence (even less than 10% with an oxaliplatin combination), gaining very few individuals.
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Patients on MET-only lost weight, while patients on other OAM combinations gained weight.
All the triplet combinations gained further efficacy after the addition of PZA.
In the decade following, gemcitabine-based neoadjuvant combinations gained popularity due to the positive findings reported by Burris and colleagues in the metastatic setting with regards to clinical benefit as well as a modest survival advantage 18.
It is worth of note that because we did not observe a differential regulation of genes downstream of the EGFR, PI3K, P53 and AKT pathways, the combination of gains at the EGFR locus and losses at the PTEN locus, found in the NL-type and not present in the HD-type of cultures, was likely not responsible for the different in vivo invasion behavior.
Loss of heterozygosity in combination with gain of the same region (Gain-LOH) is another very intriguing aberration that was found in the material, e.g. in the 17 q region often affected with gain in aggressive NB tumors.
Hence, a site can have any combination of gain and loss rates, for example, it can be fast to gain introns but slow to lose them.
The combination of gain-on-sale and securitization meant that as long as Green Tree could find more borrowers, it could report higher profits, said Mr. Crittenden, the president of Conseco Finance.
With the optimal combination, the gain can be as high as 48.1%.
