(c) Disease-specific drug combination discovery With the constructed disease signaling network and the predicted drug targets, drug combinations are then prioritized by combining the following synergistic scores.
Similar to a drug discovery cascade, the in silico output is only the start of a combination discovery cascade, wherein the subsequent progression depends on the discovery of bactericidal combinations in vitro and, finally, bactericidal combinations in vivo.
The combination of discoveries and disposals plus the prospect of a buyback of as much as €6 billion of the company's stock helped lift Eni's share price 15 percent last year.
Most of the profilers discussed in this chapter have ingeniously incorporated a combination of discoveries made in the fields of electronics, hydraulics, electromechanical engineering, and underwater acoustics.
Perhaps it's this combination of discovery and autonomy that accounts for the rise of the new female synthesists.
This combination of discovery learning and learning by surprises both aid in grasping the emergent.
An 'early' phase of learning is identified, which is supported by expository learning, whereas a 'late' phase of learning, also identified, is supported by a combination of discovery- and inquiry-based learning.
I was told that 11 days in the Western Cape was too much time, the truth is it was the perfect combination of discovery and relaxation.
Additionally, the combination of discovery approaches used provides comparative insight into commonly used quantitative proteomic techniques.
In Fig. 6 the combination of discovery and targeted metabolomic analysis is shown.
