Phase II clinical studies that explore the activity of new drugs or new drug combinations demand a rigorous evaluation of tumor response.
There could be a combination of demand and supply factors that contribute to this observation, on the demand side, the least poor may want to avoid long queues and therefore go directly to the private sector to purchase medicines.
These factors in combination promote demand for the debaters' own productions.
For the study, researchers defined job strain as a combination of demand (the amount, pace, and difficulty of the work) and control (the ability to make work-related decisions or be creative at work).
Indeed, this is exactly what has occurred in the Eastern States, where the combination of demand from export market and the addition of costly unconventional gas developments has pushed up the overall gas price considerably.
Innovation often arises out of a combination of demand pull (from consumers or businesses) and technology push (think of the new product you never thought you needed until you saw the ad).
There is a combination of demand and supply side factors constraining sustained enrolment in the CHF among the population.
Each individual matrix cell shows the optimal technology for a particular combination of demand and lot size, and the number of units required per lot (within brackets) for the final stage of the expansion process train.
Four types of jobs are distinguished in a 'Job Demand Control' model, which operates according to the combination of demands and control they offer: passive jobs (low demands, low control), low strain jobs (low demands, high control), active jobs (high demands, high control) and high strain jobs (high demands, low control).
