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Specifically, we describe a novel drug combination consisting of a cytotoxic agent (vinorelbine) with an apoptosis-inducing lipid (phosphatidylserine, PS).
In this study, we used a tripolymer combination consisting of a natural polymer, chitosan and two extracellular matrix components; collagen type 1 and hyaluronic acid to coat tissue culture plate to evaluate their effect on osteogenic differentiation of human bone marrow derived mesenchymal stem cells (hMSCs).
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Fifty eight of the 117 Lon protease-like proteins were found to possess the canonical Lon protease domain combination, consisting of an N-terminal domain (LON), a central ATPase domain (AAA+ module) and a C-terminal proteolytic domain (Lon_C).
A typical combination consists of a camel-color stole to match the sweater worn with a camel suede skirt with dirndl fullness.
The employed VHH combination consisted of a VHH binding to HER2 and a VHH binding to CAIX.
The combination consists of a first phase with tilt modifications and a second phase when the proposed algorithm is activated and the antenna tilt does not change.
The PCR primer combination consists of a forward GSP positioned in the internal sequence and the M13 primer.
The fluorometholone/tetrahydrozoline fixed combination consists of a less potent corticosteroid and a decongestant.
Further randomized trials demonstrated that doublet combinations consisting of a platinum agent plus a new cytotoxic were more efficacious than new cytotoxic monotherapy (Table 4).
For example, we identified a combination consisting of the VHS domain (IPR002014) and the UIM (ubiquitin interacting motif) domain (IPR003903).
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