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The column panels show the four different ISIs, with the spike history indicated in the top (with different times axes) of each column, and the sinusoidal stimulus for the corresponding time periods.
No specific p-PolII immunoreactive signals could be detected before late EGK-II stage (Fig. 2A, leftmost column panels).
At EGK-IV (Fig. 2A, 6th and rightmost column panels; Fig. 2C,D), p-PolII signals became more robust and positive cells became more abundant.
At late EGK-II/early EGK-III (Fig. 2A, 2nd and 3rd column panels), weak nuclear p-PolII signals were observed in a few centrally located cells.
By mid-/late EGK-III stages (Fig. 2A, 4th and 5th column panels), p-PolII signals became progressively stronger and could be readily detected in many central cells.
The proportion of cases occurring in patients with a prior infection and the proportion of averted cases increases exponentially with higher incidence rates in both the equilibrium dynamic (left column, panels A, C) and individual stochastic models (right column, panels B, D).
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In addition, the column panel zone can be proportioned to participate in energy dissipation.
Column panel zone (PZ) ductility significantly affects the failure mode of beams with reduced beam section (RBS) moment connections.
The ductility of steel moment resisting frames is developed through flexural yielding of beams, shear yielding of column panel zones, and flexural yielding of columns.
A connection shall be designed so that inelastic behavior is controlled either by flexural yielding of the beam in combination with shear yielding of the column panel zone, or by flexural yielding of the beam alone.
Design limit states including plate bending, column and panel buckling, panel ultimate strength, and plastic analysis.
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