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Microbiological analyses performed on ceftaroline-loaded films demonstrated that the antibiotic was released in an active form, decreasing the microbial adherence rate and colonization of the surface.
Development of P. furiosus and Methanopyrus kandlerii bi-species biofilms was shown to be established within less than 24 hours on biotic surfaces [12].However, the formation of a layered biofilm was dependent on the initial colonization of the surface by M. thermoautotrophicus cells to which P. furisous could adhere by using its flagella and establishing cell-to-cell contacts.
Coating of implants with antimicrobial substances could avoid or limit colonization of the surface and thereby reduce the risk of biofilm formation during severe infections.
Coating of implants with antimicrobial substances may avoid colonization of the surface by microorganisms and reduce the risk of biofilm formation and clinical infections.
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Bacterial biofilms and bacterial colonization on the surface of implanted devices in vivo might lead to clinical infection [ 5– 8].
Consistent with our findings, the TFP of different bacteria can bind to a variety of surfaces, including inert surfaces, bacterial cells, and eukaryotic cells, and can mediate both colonization of the surfaces and intimate contact through pili retraction [7], [35].
Sparse colonization of the substrate surface by bacterial cells was observed.
However, the risk of colonization of the stickers' surface has not been evaluated.
Scanning electron microscopy revealed the rapid microbial colonization of the films' surface.
Understanding the colonization of the land surface by plants requires us to identify if special geochemical circumstances had arisen to promote it, or if it was simply an aspect of a wider diversification of life into new niches.
Most important in the pathogenesis of infection is the colonization of the device surface and the consecutive formation of a biofilm (Zimmerli and Moser 2012; Gosheger et al. 2004), in which Staphylococcus aureus and koagulase-negative Staphylococci are most frequently implicated as the etiologic agents (Zimmerli and Ochsner 2003; Hunter and Dandy 1977).
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