However, more distal colonic disease (distal third of the colon) or the potential for malignant transformation may not be represented at this sub-locus.
Two-thirds of patients have only left-sided colonic disease with sparing of the right colon.
The analysis showing the enrichment of colon eQTL among SNPs associated with colonic diseases supported the usefulness of colon eQTL as a tissue-specific tool to improve understanding of colonic disease susceptibility.
The utility of colon eQTL for studying the genetic basis of inter-ethnic differences in colonic disease risk was demonstrated by showing their enrichment for SNPs that exhibit high allele frequency differences between European and African populations.
Forty percents of patients had a colonic disease, 21% had small intestinal lesions only, 30% had lesions in colon and small intestine while 9% had a predominant perianal disease.
Simultaneous treatment of incisional hernias in patients with colostomy or colonic disease remains a difficult challenge, considering the reluctance of most surgeons to treat both conditions at the same time, especially when prosthetic repair is needed.
In Western countries, diverticulosis is the most common colonic disease and harbours many traps in colonic imaging with CTC.
The purpose of this book is to explain the current state of the art in radiological examination, interpretation, and understanding of colonic disease.
The following information also assists in the selection process: the location of the tumor, existence of colonic disease, age, comorbidities, and the baseline bowel/sphincter function [24].
In line with the Montreal classification (4) three subgroups were defined: ileal disease only (L1), colonic disease only (L2) and ileo colonic disease (L3).
