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Archived formalin-fixed paraffin-embedded tissue blocks from the primary colon resection specimen and the matching resected CRLM were sectioned (5 μm), mounted on APS-coated slides and anonymised by a coding system that preserved the within-patient matched-pair design.
Paired tissue samples were taken from the tumoral area and the macroscopically unaffected, adjacent, colonic mucosa of 14 patients who underwent colon resection for sporadic CRC at the Tor Vergata University Hospital (Rome, Italy) and used for Smad7 evaluation by western blotting.
In addition, he required sigmoid colon resection and stoma formation after mesenteric metastases caused colonic obstruction.
Subjects (10) undergoing colon resection for colon cancer (age range 35 84 years); each sample of normal colonic mucosa was collected at a distance of at least 12 cm from the edge of the tumour.
Colon resection.
Laparoscopic sigmoid colon resection was performed.
Thirty-two patients were treated with Seprafilm and 30 received no treatment following their colon resection.
Elective surgery included segmental resection of the sigmoid colon, resection and repair of the bladder dome.
Natural orifice endoscopic full-thickness colon resection attempts to overcome the need for invasive surgery in selected colorectal indications.
Classic emergency surgical management of complicated perforated sigmoid diverticulitis is based on the principle of a two-stage operation, with colon resection and temporary stoma (Hartmann's procedure).
A significant decrease of sigmoid mural thickening and resolution of perivisceral acute inflammatory changes are observed (d e), allowing limited laparoscopic sigmoid colon resection to be performed.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com