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It is actively produced in the posterior chamber by the non-pigmented ciliary epithelium and flows anteriorly through the pupil and reabsorbs through the collector channel in the angle.
7 Previously we reported that Schlemm's canal (SC) cross-sectional area (CSA) as measured from spectral-domain optical coherence tomography (SD-OCT) is much smaller adjacent to collector channel ostia (SC collector channel branch points).
With the Trabectome, the scleral wall of Schlemm's canal with its collector channel openings is exposed to direct aqueous flow.
Aqueous outflow vascular structures and SC collector channel ostia were used as landmarks to identify a reference location within the limbus.
In our 2010 publication, we were not attempting to provide an overall characterisation of SC, but only to test a clinical observation of SC expansion at the location of collector channel ostia.
Newer Schlemm's canal surgery involves insertion of stents into the canal to bypass the trabecular meshwork [ 12, 13]; proper placement of stents in relation to Schlemm's canal collector channel ostia is likely to be important to success of the procedures.
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Also, 78 % of all patients had intraoperative reflux bleeding from the collector channels.
Collector channels in the scleral wall of Schlemm's canal are exposed to the anterior chamber and recruited for aqueous drainage into the scleral and episcleral venous plexus.
Further experimental studies will be essential to better understand the transport and resorption of aqueous humor across the collector channels and the complex downstream draining and vascular system.
Using vasculature and collector channels as landmarks, one location contained in each of the three scan volumes was identified and used to ensure that the same region of the limbus was analysed throughout.
Canaloplasty is a new non-penetrating glaucoma method using a 360° microcatheter dilation of Schlemm canal and a tension suture to restore the normal aqueous outflow pathway through Schlemm canal and the collector channels.
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