Collectively, the identification of SORT1 and TNF receptors as PGRN receptors will open new avenues in PGRN cell biology research and therapeutic development.
Collectively, through the identification of IL1A as a p63 target gene, we discovered a role for p63 in regulating paracrine signaling pathways between epidermal keratinocytes and dermal fibroblasts.
These findings collectively indicate that identification of miR-34a as a potent tumor suppressor is a highly significant finding with respect to the development of potential therapeutics for cancer.
Several algorithms are introduced, collectively called RE-Identification of Data In Trails (REIDIT), which link genomic data to named individuals in publicly available records by leveraging unique features in patient-location visit patterns.
Taken collectively, our study enabled an identification of a limited set of molecules particularly associated with either dysplasia or advanced MAPK induced adenocarcinomas.
Molecular Weight Search MOWSEE) scores [80], number of matched ions, percent protein sequence coverage, and correlation of gel region with predicted mass and pI were collectively considered for each protein identification.
Collectively, these results suggest that identification of mechanism(s) responsible for the elimination of wild-type P53 mRNA requires more research.
Even though this difference may be partly due to the method of QTL-identification, the findings collectively suggest that disease resistance is strongly affected by epistatically interacting loci that are not additive loci.
Collectively, this finding suggests that by identification, stimulation and isolation of ultrafast cycling cells from a known cell line (e.g., stem/progenitor cells) iPSC generation could be achieved in a deterministic level.
Regardless, these data collectively validate our approach for the identification of AMD-related genes, and demonstrate that genes within the RPE-choroid Global Up disease module are global biomarkers of AMD.
