Collectively, SAM analysis provided a collection of genes that are differentially expressed in each model.
Collectively, this analysis supports the conclusion that Hsp42 functions to collect aggregates into the age-associated protein deposit structure, whereas Hsp104 functions to disaggregate/refold age-associated protein deposit destined substrates.
Collectively, the analysis of PARP3 genomic occupancy supports the idea that PARP3 regulates transcription during development.
Collectively, our analysis suggests that increasing AP repertories might be an important factor in shaping human genome, transcriptome and diseasome.
Collectively, this analysis indicates that the biochemical characteristics of ligands in the bioactive fraction (Fig. 3) are inconsistent with those of previously identified pheromones (see Table 1).
Collectively, our analysis of core histone modification sites here, albeit still incomplete, will be invaluable for future studies of histone modifications in plant genetic and epigenetic regulation.
Collectively our analysis suggests that in ES cells and most likely during development, graded levels of activated Smad2/3 effectors are converted proportionately into several target gene expression and that these responses remain sensitive and reversible over a 24 hour period.
Collectively, proteomic analysis of plasma identified known acute phase proteins, proteins linked to inflammatory regulators such as TGFβ, and additional proteins (e.g. cytoskeletal proteins actins, cofilins, vasp, profilin, and destrin) not previously linked to inflammation (Table S1).
Collectively our analysis of the transcriptional response to PH reveals that lack of UPF2 leads to a block in liver regeneration at a stage before dedifferentiation and entry into the cell cycle and further underlines the strong requirement for UPF2 in proliferating cells.
