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But as the orphan drug business model becomes increasingly popular among pharmaceutical companies, the collective cost of the drugs is beginning to mount.
Yes, they're ugly, and their prospects are uncertain, but taken as an entire portfolio, they will almost certainly out-earn their collective cost.
The report puts the collective cost to the nation over the working life of each high school dropout at $292,000.
Workers represented by public sector unions will not be able to benefit from union representation without bearing their share of the collective cost.
Whether it be feasting on carbohydrates or playing dangerous sports, a free society allows its members to pursue pleasures that are injurious to their health, even if this increases the collective cost of health care.
Max Mosley, who is keen to cut expenditure in formula one, made the teams spend the winter developing an energy-recovery system, at a collective cost of many tens of millions of pounds.
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The agency is reviewing four additional projects, Mr. Cestero said, but their collective costs would exceed the program's remaining financing.
As the epidemic of obesity grows, our country faces higher collective costs for the treatment of associated diseases like diabetes and heart disease.
It is axiomatic among economists that the collective costs to the neighbours from protectionist laws are unacceptably large compared to the benefits enjoyed by the protected.On the campaign trail, populist rhetoric serves as a distraction.
Mr. Trippler said he was surprised by Northwest's attempt to charge more for some tickets, given that the airline industry has had almost no luck in trying to raise prices to cover the high price of jet fuel, which has raised their collective costs by billions of dollars this year.
To curb the sale and manufacture of drugs because of expense, or making fatuous equations of the price of health care in such terms, ignores the history of medicine and the purposes of treatment: to extend the care and life of people without regard to individual merits or even the collective costs to society.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com