Data collection included histological and immunohistological identification of tissue types, and mean collagen fiber angles and angular conformity between individual fibers in superficial, intermediate, and deep zones within the cartilage.
Although some correlations may be specific to cancer status, this dataset represents a large collection of different tissue types.
Even with the collection of different tissue types in our study, there are still likely to be undetected variants.
Some studies have shown that the osteogenic potential of MSCs may vary as a function of tissue type [ 3],[ 4], collection site [ 5], animal species [ 6], age [ 7],[ 8], state of health [ 9], and performance of physical activity on a daily basis [ 7],[ 10].
Enthusiasm for the recruitment of donors and the systematic collection of donor tissue typing was ignited by Shirley Nolan in the 1970s in the United Kingdom.
When this characterization also addresses natural person-to-person variability of the tissue optical properties, a wide range of tissues types are of clinical interest for data collection.
The large collection of tissue and cell type specific models in the TSEM may facilitate the integrated modeling of metabolic interactions such as those between adipocytes and macrophages, different brain tissues, and between tumor and stromal microenvironment.
After verifying that our new liver model could show similar or better coverage and functionality when compared to state-of-the-art models and algorithms, we next took advantage of the automated and computationally efficient nature of mCADRE to generate a large collection of tissue and cell type specific metabolic models.
Secondly, collection of tissue samples in post-mortem requires consideration of several novel factors not relevant when examining other tissue types – such as cause of death, post-mortem RNA integrity and post-mortem interval [ 20].
Wild-type tobacco plants (Nicotiana tabacum cv. Samsun) were used for the collection of tissue samples for all downstream studies.
The Autopsy Service maintains a collection of tissue for educational purposes.
