Today she lives alone, in a first-floor flat in north-west London, surrounded by pot-palms and photographs of Ugandan friends and relatives, many of whom have died of Aids - or acquired immunity deficiency syndrome, the collection of illnesses such as TB and pneumonia that can kill when the body's immune system has been damaged by HIV.
Moreover, as Littré saw this collection of illnesses as a single disease, he essentially turned it into an epidemic, probably because he had the modern sense of the term in mind and thought that Hippocrates had observed and described an epidemic illness unknown to modern medicine (5 ).
Due to the subjective diagnostic criteria, unknown causes, and non-specific symptoms, many clinicians consider FM to be a collection of ill-defined illnesses.
Main outcome measures Vaccine effectiveness calculated as 1− odds ratio for influenza in vaccinated (received pandemic H1N1 vaccine at least two weeks before onset of influenza-like illness) versus unvaccinated participants), with adjustment for age, comorbidity, province, timeliness of specimen collection, and week of illness onset.
Negative values indicate that the time of sample collection was before that of illness onset.
The collection of ICU acuity of illness scores is labour intensive and therefore costly.
Median timing of sample collection from the onset of illness was 8 days (range 1 21).
In results above, the model estimates are based on log2 (titers), to which the time of convalescent-phase serum collection (in weeks postonset of illness, starting from week 3) contributed in 3 terms; the antibody rise follows the first order of weeks postonset, and decay follows the second order of weeks postonset and an interactive term between duration of illness and weeks postonset.
14 15 The development of electronic data collection systems in emergency and pre-hospital care raises the potential for routine collection of measures of severity of illness and their incorporation in risk adjustment models.
