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Collection of compounds with small molecular weights (250-450 D) to provide room for further derivatization.
Yale Compound Repository is a collection of compounds synthesized by Yale chemists.
A new collection of compounds, called "bryologs" – derived from a tiny marine organism – activate hidden reservoirs of the virus that currently make the disease nearly impossible to eradicate.
The peel extracts consisted of a collection of compounds including fatty acid esters (FAE), phenols, coumarin derivates, terpene derivatives, being the most concentrated osthole, isogeijerin, hexadecane and squalene.
A collection of compounds, structurally related to the anticancer drug tamoxifen, used in breast cancer therapy, were designed and synthesized as potential anticancer agents.
The method was evaluated against a collection of compounds assayed previously against a cyclin-dependent kinase target, CDK-2, starting with 23 X-ray co-crystal structures.
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Using DoDAF, we describe a method for defining projects as a collection of compound real options.
However, also self-organizing ontology construction depends on the manual collection of compound training and test sets to compute chemical class definitions.
A comparative analysis of gene signatures derived from a large collection of compound treatment experiments can identify those compounds with similar biological properties, pinpoint treatments with toxic side-effects, and discover novel indications for existing compounds [11].
Furthermore, by exploring a large collection of compound signatures, investigators can identify chemical perturbations that can activate or deactivate cell type-specific differentiation programs and use them as additional tools in future experiments.
Successful screening campaigns depend on large and structurally diverse collections of compounds.
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