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All of these recent studies of genetic fidelity found genetic aberrations in iPSC lines, but they existed at relatively low frequencies, and the collection of aberrations in any two lines rarely appeared to overlap.
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Here the natural successor to Bradley was Friedrich Wilhelm Bessel, who reduced Bradley's enormous collection of star positions for aberration and nutation and in 1818 published the results in a new star catalog of unprecedented accuracy, the Fundamenta Astronomiae ("Foundations of Astronomy").
On the basis of these studies, a collection of genetic and epigenetic alterations, chromosomal aberrations, gene mutations and altered molecular pathways were described [ 183].
Here we report multiple genome aberrations in a collection of 78 CML and 14 control samples by oligonucleotide array comparative genomic hybridization.
By studying a sufficiently large collection of cancer samples, Significant Copy Number Aberrations (SCAs), defined as significantly recurrent CNAs that affect the same region in multiple tumors, are widely considered as informative surrogates of "driver" mutations that may help pinpoint novel cancer-causing genes [ 3, 9].
"Until the last couple of years, the game didn't have a whole lot of aberrations.
Similar to the fitted aberration function, these images are improved but not yet free of aberrations.
All distributions of aberrations were overdispersed.
The number of cells with aberrations and the number of aberrations were recorded.
The number of aberrations varied individually from 0 to 25 aberrations per 100 cells.
Two types of aberrations are considered: (A) aberrations of height 1.5 and length 10 probes and (B) aberrations of height 1.0 and length 30.
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