HRA contributed to the planning of the study, data collection (exposure classification), interpretation of results and drafting of the manuscript.
JW, PAJ, TW, and VV provided technical input to data collection, exposure assessment, data analysis, and manuscript preparation.
Although we lacked exposure information over the entire meiotic period (about 3 months prior to collection), exposure monitoring overlapped with the timing of the two meiotic divisions (about 35 days before semen collection) when aneuploidy would be generated.
To achieve these objectives, the project uses innovative research methods including a longitudinal assessment of travel and PA behaviour, electronic and web-based data collection, exposure-adjusted assessment of crash risk from AM, innovative sensors for travel behaviour, PA and crash locations, and improved knowledge of acute health effects of AM and exposure to air pollution.
Information collected from each study was organized into four main categories: basic information, data source and period of collection, exposures, and outcome measures.
"Y" or "N," designating "yes" or "no," was attributed to the types and periods of data source collection, exposures, and outcomes studied.
Information collected from each study was organized into four main categories: basic information, data source and period of collection, exposures, and outcome measures and was coded and entered into an Excel spreadsheet.
The authors listed several potential explanations, including logistics of the sample collections, exposure in other microenvironments, and exposure via inhalation.
It is difficult to investigate very early miscarriages using prospectively collected exposure information, since the time period, in which collection of exposure information must take place, that is the time from detection of pregnancy to the occurrence of an early miscarriage, is short.
The epidemiologic challenges inherent in exploring linkages between chronic OP pesticide exposures and adverse health outcomes may likely be attributable to the collection of exposure data that are not representative of true exposure.
A possible disadvantage with a case-control study with retrospective collection of exposure data is the risk of misclassification of exposure due to recall bias.
