This problem is becoming especially frequent in studies using bio-logging to collect interaction data, which is an approach used particularly frequently in the construction of animal networks.
We collected interactions whose rank was at least one standard deviation above the mean rank calculated over all parameters.
The HINT database collected interactions from several databases and filtered them to remove low-quality interactions.
From ProLinks [ 44] we collected interactions obtained by the phylogenetic profile method.
Figure 6 illustrates the collected interactions from a KEGG gene set involved in the T cell signaling pathway in human, where the post-transcriptional regulatory relationships are drawn as blue lines.
Once a developer embeds Pathmapp's technology (in one line of code), it begins collecting every interaction (touch, swipe, etc).
Recently, much effort has been put in to collecting binary interaction data (e.g. Rual et al., 2005) to dissect PPI networks.
STRING is a comprehensive database, collecting the interactions from well-known resources, such as MINT, HPRD, BIND, DIP, BioGRID, KEGG, NCI-Nature Pathway Interaction, among others [30].
IntAct (2) is a database collecting protein protein interactions.
The Search Tool for Retrieval of Interacting Genes/Protein (STRING) database [ 27] was used to collect protein interaction data to construct disease-protein network (DPN) from 1209 seed genes.
