Processing a single chromosome and sample took between 5 min and 4 h (chrY vs. chr1), and a final merging step to collate datasets from all samples into one tally file took up to 35 h to complete when using compression.
Participants were receptive to the idea of a new limited dataset collating comparative data from currently available routine data sources.
The advantage to this approach is clearly the ability to collate large datasets fairly cheaply, from investigators who are willing to share.
When Hindorff et al began collating their dataset they only included one SNP in each associated region whereas the Johnson dataset include all of them.
Secondary analysis refers to some re-analyses of data collected by other researchers or organizations originally, including the analysis of datasets collated from a variety of sources to create time series or area-based datasets (Hakim, 2000).
This is based on the comparison between the large scale dataset generated by Belle et al. and a smaller dataset collated from values reported in the literature, where the distribution of fold different values centres nearly perfectly around one.
Polypharmacology profiling requires carefully collated, large datasets.
Finally, we collated these datasets to a master list of 749 cancer-associated genes Additional File 2. We retrieved expression data from massively parallel signature sequencing (MPSS) covering 182 719 tag signatures across 32 tissues [ 45].
We collated a dataset of 13 693 trees from 390 plots in wood-pastures from eight different European regions (western Estonia, eastern Greece, northern Germany, Hungary, northern Italy, southern Portugal, central Romania, and southern Sweden), including tree diameters at breast height, tree density, management type, and tree species composition.
Multiple linear regression analysis was applied to a dataset collated from the literature.
