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Focal salvage therapy (FST) limits collateral tissue damage and may improve therapeutic ratios.
No collateral tissue damage was seen at treatment energies of 750 and 1000 J.
However, low specificity of neutrophil antimicrobial armaments allows for collateral tissue damage.
However, NETs can also activate endothelial cells and induce collateral tissue damage in the lungs, heart, and liver [47, 48].
The anti-VEGFs are also effective in the management of subfoveal or juxtafoveal neovascular membrane as they also reduce the collateral tissue damage to neurosensory retina and choroid as is seen with PDT or laser photocoagulation or submacular surgery [20].
Here, we discuss the shared features involved in the immune response to infection and cancer including modulation by commensal microbiota, reactive hematopoiesis, chronic immune responses and regulatory mechanisms to prevent collateral tissue damage.
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Sections of malignant and collateral tissues were reviewed and analyzed by a senior gastrointestinal pathologist blinded to patient outcomes.
IGRT allows oncologists to use tight RT treatment margins around tumours helping minimise the risk of collateral normal tissue damage.
To avoid collateral thermal tissue damage any char formation was removed with saline gauze.
Products of these cells (enzymes, profibrotic mediators including transforming growth factor-β) contribute to collateral lung tissue damage 4, 5. Persistent and unresolving airway inflammation cumulates in a variety of alterations to airway architecture.
A neodymium-doped yttrium-aluminium-garnet laser has been used in an experimental, robot-assisted radical prostatectomy in canines in an attempt to reduce collateral nerve and tissue damage, whilst the erbium-doped ones are starting to be used in cosmetic skin resurfacing.
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