The treatment of certain non-melanoma coutaneous toumors with imiquimod 5% cream, has been effective, without collateral effects; erythema, edema, vesicles, crusts and erosions with itching or burning in the application area, have been the most frequent adverse events which however did not cause the suspension of therapy.
The available chemotherapy for this illness includes two nitroheterocyclic agents, nifurtimox and benznidazole, which are effective against acute infections but show poor activity in the late chronic phase, with severe collateral effects and limited efficacy against different parasitic isolates.
Unlike mechanical obstruction of the thoracic duct, where the development of lymphaticovenous collaterals channels provides lymphatic drainage, generalized central venous hypertension caused by cardiac disease prevents the development of an effective collateral flow.
Some companies, like Apple, have found workarounds -- such as borrowing money to fund domestic purchases, using the offshore cash as effective collateral.
It's an old story that's not often told or told well in Hollywood, but this year's Sundance Film Festival premiered two films --Smashed and Predisposed -- that showcase addiction and all its glorious collateral damage with effective grace and a deft touch, thanks to some outstanding writing and performances.
Concerning the pathological function of the COW for providing effective collateral perfusion, when the diameters of the vessels constituting the COW were less than 0.5 mm, the vessels can be regarded as absence.
The dissenters also argued that the Fed's other efforts to restore confidence among lenders — including its decision to provide cheap loans to investment banks in exchange for relatively risky collateral — were a more effective and time-sensitive approach to improving the economy.
The development of an effective collateralization in the ischemic zone involves angiogenesis, which is the sprouting of new capillaries, and arteriogenesis, the development of arterial structures from small preexisting collateral vessels [19].
MMC III, IV and V targeting in periampullary cancers is mechanistically viable based on their characteristic expression profiles, indicating that such targeting strategies can be selective and therefore likely to be effective with minimal collateral damage to benign pancreatic tissue.
The couple had rejected conventional radiotherapy offered in Britain, believing proton beam treatment was more effective in limiting the collateral damage to other organs, and would lead to less severe long-term side effects for Ashya.
