Exact(4)
The collapsed dataset was normally distributed (Kolmogorov-Smirnov test = 0.162, p = 0.100).
One of the consequences of this strategy is that the collapsed dataset generated by this procedure preserves periodic patterns associated with the segmentation clock, while it may affect most other patterns (such as a linear increase with developmental time).
A Poisson GLM model can then be fitted to the collapsed dataset, giving identical parameter estimates to a Poisson GLM fitted to the non-collapsed dataset.
This main analysis used the means of residuals for individuals in a collapsed dataset (one record per child).
Similar(56)
The overlap pair analysis was performed using collapsed datasets obtained for sugar-fed mosquitoes allowing two mismatches.
GSEAs for the five signaling pathways and the positive control tissue(s) were run using GSEA software http://www.broad.mit.edu/gsea/ at the probe level (Collapse dataset to gene symbols = false) with 1,000 gene set permutations.
Given this condition, it is possible to 'collapse' each split dataset across covariate patterns (for example, separately collapse the dataset for males and females) [ 30].
In addition the average growth velocity for each child over the first year, obtained through collapsing the dataset to child level was used.
After collapsing the dataset from adjusted probes to symbols by GSEA, the expression levels of 2,870 of 5,923 genes were changed in the WAT of FSP27-/ mice (48.5%).
β4 phenotype was compared to mock phenotype by first collapsing the dataset to gene symbols and then using a weighted, difference of classes metric for ranking genes.
In the present study we used GSEA version 2.0.12 (www Broad Institute at MIT), with the C2 curated canonical pathway gene set (i.e. c2.cp.v3.1.symbols.gmt download), collapsing of dataset to gene symbols, weighted enrichment statistic and real gene list sorting.
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