Post-transcriptional control of gene expression is mostly conducted by specific elements in untranslated regions (UTRs) of mRNAs, in collaboration with specific binding proteins and RNAs.
However, in both pathways, cellular collaboration depends on the binding and subsequent processing of antigen, interaction via complementary pairs of adhesion molecules, and a certain milieu of immuno-modulatory cytokines, alterations of which may contribute to abnormalities in pSS [ 59, 60].
This property relies in the presence of four canonical HS-binding sites located at the C-ter domain but requires the collaboration of a HS-binding site located in the core of the protein.
The Langmuir model recommends a monolayer uptake of the adsorbate onto homogeneous surface of biosorbent, having equal adsorption energies for all available binding sites without any collaboration between the biosorbent (Sawalha et al. 2006).
These versatile properties of aaRSs are the outcome of their differential cellular localization, nucleic acid binding properties, protein-protein interactions and collaboration (fusion) with additional domains.
This problem was overcome when, in collaboration with Alex Sette from the La Jolla Institute of Allergy and Immunology, a PanDR binding motif predicting computer algorithm that predicts binding to all HLA-DR genotypes was used [ 67].
It was also found that a large number of transcription factors had binding sites co-enriched with ERα binding sites, which indicated a close collaboration between ERα and other factors.
It allows a protein with a single Hsp70/Hsp90 binding motif to simultaneously recruit multiple chaperones and foster their side-by-side collaboration.
In collaboration with the University of Pennsylvania, a 222Rn emanation source was used for the determination of the binding affinity of radon to a cryptophane molecular host.
The similar binding profiles and regulatory capacities of Xbra, Eomes, and VegT encouraged us to explore potential collaboration between these T-box TFs in paraxial mesoderm formation.
