Sentence examples for collaborate to regulate from inspiring English sources
In a regulatory module with two TFs, if both TFs collaborate to regulate the same target genes, the down- regulation of both TFs should have significantly different phenotypes from the down-regulation of each individual TF.
We suggest that catalyzed protein exchange may be a general feature of dynamic macromolecular machines and propose a hypothesis for how substrates, Nedd8, and Cand1 collaborate to regulate the cellular repertoire of SCF complexes.
The extracellular matrix and integrins collaborate to regulate gene expression associated with cell growth, differentiation and survival; all of which are deregulated during cancer progression and metastasis.
In addition, Sonic hedgehog (Shh) and Wnt pathways collaborate to regulate cell cycle progression via the production of early and late cyclins in neural progenitor cells.
In that study, 52% of TCF3 target genes were also bound by Ikaros, suggesting that these two transcriptional factors collaborate to regulate B-cell specification.
It has been found that the three core transcription factors (TFs) NANOG, OCT4, and SOX2 collaborate to regulate pluripotency and self-renewal of human ES cells in the form of a regulatory circuitry [ 2].
"This work is where the executive brain comes from: the ability to think ahead, to collaborate, to compromise, to regulate ourselves," said Cook.
The filamentous phenotype in the pseudodiploid was suppressed by gcn5Δ, but the induced FLO11 expression by 3AT in the pseudodiploid was similar to that in haploids (data not shown), so cell-type-specific factors other than mating loci may collaborate with Gcn5 to regulate ncRNA expression.
Many remodelers collaborate at gene promoters to regulate transcriptional competency.
Thus, it is interesting to speculate that in other tissues, alternative bHLH-type transcriptional activators could collaborate with c-Jun to regulate enhancer activity through a similar mechanism.
The red boxes of the dotted lines represent the time points when the TFs collaborate with each other to regulate the target genes.
