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The phantom contained hot spheres (inner diameters 10, 13, 17 and 22 mm), cold spheres (28 and 37 mm inner diameter) and a lung insert (50 mm diameter).

The average (and range) percent contrast obtained for hot and cold spheres, the average (and range) standard deviation of the background counts, and the mean residual error in scatter and attenuation corrections were evaluated.

The average and range of percent contrast obtained for hot and cold spheres, the average and range of the standard deviation of the background counts, and the mean residual error for the scatter and attenuation corrections were evaluated.

TOF increased both hot and cold sphere contrast.

The cold sphere CRC was also significantly improved.

In general, PSF increased hot sphere contrast, but not cold sphere contrast.

Note the presence of two phases in the convergence rate for the cold sphere.

The TOF option on the mCT improved lung residual error and cold sphere contrast.

These features made the improvement especially noticeable for the cold sphere and the three smallest hot spheres (Table 2, Figure 2).

For the MEPH collimator, the largest possible circular orbit was used in order to get the maximal transverse FOV. Figure 1 Hot and cold sphere phantoms.

Fig. 3 Contrast vs background variability with increasing number of iterations (2 8, left to right) and with different reconstruction settings for the Biograph mCT and mMR system; 10-mm hot sphere, 1 8 ratio (a), 37-mm cold sphere, 1 8 ratio (b), 10-mm hot sphere, 1 4 ratio (c) and 37-mm cold sphere, 1 4 ratio (d).