Sentence examples for cold preservation solution from inspiring English sources

Even hypothermic machine perfusion, which has been designed to deliver cold preservation solution into the organ via the circulation, may be incapable of delivering adequate oxygen to an organ during preservation, particularly when the perfusate does not have substantially higher oxygen carrying capacity than water and it is not saturated with a gas containing higher oxygen fraction than air.

More controversial practices are the administration of thrombolytics and antemortem cannulation in preparation for the administration of cold preservation solution.

The addition of a Melatonin and Trimetazidine cocktail to the cold preservation solution improved steatotic liver graft preservation through AMPK activation, which in turn reduced ER stress and increased autophagy [ 41].

The inhibition of autophagosome formation and maturation by adding the autophagic inhibitor Wortmannin and LY294002, a specific inhibitor of PI3K/Akt kinase pathway, to the cold preservation solution attenuated liver dysfunction and recipient mortality rates [ 33].

METHODS: Livers were obtained from rats pretreated with three well-known antiangiogenic agents (minocycline, interferon alfa-2b, and fumagillin) and were stored for various durations in cold preservation solutions.

Storage of kidneys with cold preservation solutions containing CO-RMs also improved their function upon reperfusion [ 115].

Cold ischemia is observed during liver transplantation in which the graft is subjected to warm and cold ischemia followed by a warm reperfusion phase; the warm/cold ischemia sequence is due to vascular occlusion of the liver graft during its procurement from the donor and to graft storage in cold preservation solutions before liver transplantation [ 2, 10].

They are particularly susceptible to mitochondrial alterations after storage in cold preservation solutions for transplantation [ 102, 103].

Perfusion is started with a cold hepatic preservation solution and the venous effluent is actively sucked from the IVC to prevent excessive body cooling.

Skeletal muscle tissue (2 mg) was placed in cold biopsy preservation solution (BIOPS) consisting of 50 mM K+-MES, 20 mM taurine, 0.5 mM dithiothreitol, 6.56 mM MgCl2, 5.77 mM ATP, 15 mM phosphocreatine, 20 mM imidazole (pH 7.1 adjusted with 5 N KOH at 0°C), and 10 mM Ca-EGTA buffer.

Livers of larger animals such as monkeys (Olinga et al. 1998a) or dogs (P. Olinga, unpublished data) should preferably be perfused with ice-cold organ preservation solution (e.g. University of Wisconsin Organ preservation solution (UW) (Belzer et al. 1990).