Coinciding with the timeframe of this study, there was debate on the definition of refractory CM (due to the introduction of onabotulinumtoxinA as a preventive treatment), resulting in a proposal from the European Headache Federation Expert Group to modify the definition to also include patients who had contraindications to or no effect from onabotulinumtoxinA treatment.
This behavior was not as prevalent in M. sexta that fed on leaves elicited 2 h prior to the experiment, suggesting that the caterpillars could be responding to a cue specifically associated with the early plant defense response; this timeframe coincides with peak accumulation of JA and JA-Ile.
The diversification within the M. namaquensis species complex also coincides with the timeframe proposed for the rapid radiation within the African Murinae [ 3].
This timeframe coincides with the expected realization of the objectives enshrined in the State Programmee of Poverty Reduction and Sustainable Development 2008-20155) (SPPRSD) which is aligned with the Millennium Development Goals (MDGs).
There were no significant spatio-temporal clusters of high rates of pneumonia found to predate or coincide with the timeframe during which there was widespread respiratory disease in finisher pigs in the province [ 1- 6, 40].
However, the timeframe coincides with the occurrence of the '1930s Dust Bowl' (Schubert et al. 2004) with most of the decade characterized by extreme drought, dust storms and catastrophic vegetation failure, with the environmental repercussions presumably tapering out over the next decade.
The majority of bat flies (72.5%) were captured on the glue boards during timeframe 1 (1715–2315 hrs), coinciding with the foraging flight of bats (Figure 5).
Our review of the colonial medical literature established that GUD, particularly syphilis, chancroid, and LGV, peaked in the relevant cities, in the period 1910 35, with incidences 1.5 2.5 orders of magnitude higher than in mid 20th century, coinciding in time with the narrow timeframe of the emergence of epidemic HIV groups.
This timeframe roughly coincides with the onset of the Pleistocene glacial periods as well as the end of the major tectonic uplift of the Himalayas22,23, suggesting that geographic isolation may have played an important role in the initial divergence of the two lineages.
It is true that there was a steep drop in the population of Europe in the mid-6th century, a timeframe that coincides with what is commonly referred to as "the Dark Ages" (a period of time spanning several centuries after the fall of the Roman Empire, from which there are few historical records of events in Europe).
We did not find a significant association between region and season for the lung condemnation data, and the predicted trends in lung condemnation rates did not coincide with the expected timeframes during which respiratory diseases were high in any of the agricultural regions in Ontario.
