Instead of choosing an arbitrary score threshold, a threshold learning mechanism based on criteria such as coherence of GO term could be incorporated, or an edge-weighted network may be used.
Then, common power and phase coherence of these periodic terms are calculated from the cross-wavelet spectra (XWT) and wavelet-coherence (WTC) respectively.
Quantitative bisulphite validation studies confirmed our ability to discriminate differences in methylation in these samples, and the biological coherence of results in terms of functional pathway relatedness is suggestive of underlying changes in epigenetic regulation as a response to IUGR.
First, we examine the coherence of the GO terms in our modules using the semantic similarity score calculated by G-SESAME [ 38].
MacCormick 1984 views coherence in terms of unity of principle in a legal system, contending that the coherence of a set of legal norms consists in their being related either in virtue of being the realisation of some common value or values, or in virtue of fulfilling some common principle or principles.
Thus, to better assess the quality of a PPI dataset by coherence of informative GO term annotations, we need to compare the percentage of coherently annotated PPIs in the dataset to appropriately generate random PPI datasets.
Our ranking algorithm, while largely empirical at this stage, identified a ranked list of genes with obvious coherence in terms of functional gene networks.
However, we noticed that coherence of PDBTM‐based dataset with WDG classification in terms of spatial similarity did not implicate coherence in terms of sequence features (see Additional file 1: Figure S1 and Additional file 3: Figure S3).
We also compare HyMR with Phoenix++, a state-of-art implementation for systems with hardware-managed cache coherence in terms of scalability and sustained to peak data processing bandwidth, where HyMR demonstrates improvements of a factor of 3.1× and 3.2× respectively.
Our review shows some coherence in terms of the direction, magnitude and statistical significance of the associations between mortality and hospital admissions for several diseases examined.
