Afterwards, focus-group interviews were conducted among experts and teachers to investigate the practicality of the framework, the structure of descriptors, and the coherence of expressions.
As no chip replicate was included in our experiment we decided to filter the probes according to the coherence of their expression profiles.
In this case the metabolic coherence directly measures the coherence of the expression pattern with the pattern of metabolic fluxes.
We can thus evaluate the likelihood of a motif being biologically meaningful by the coherence of the expression profiles of all the target genes associated with the motif.
Here, we analyze the coherence of gene expression patterns and a reconstruction of human metabolism, using consistency scores obtained from network and constraint-based analysis methods.
Consistency and coherence of gene expression data across multiple sites depends on several factors such as platform (oligo, cDNA, etc)., environmental conditions at each laboratory, and data quality.
For each biological duplicate time course, all samples were removed from the same culture to ensure coherence of gene expression between unstressed and stressed cultures.
Numerous dense network clusters show evidence of dedicated functions, such as spermatogenesis and immune response, that are clearly consistent with the coherence of the expression patterns of their constituent gene members.
The purpose of the present study is to model changes and coherence of gene expression in cerebral cortex, brainstem, hippocampus, and hypothalamus in order to obtain a broad view of brain ontogeny throughout the second half of gestation.
As a proxy of expression coherence, the averaged Pearson correlation coefficient (PCC) was evaluated for each module.
