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However, an interaction effect between age and cognitive severity was identified.
The amount of home-help services used did not reflect cognitive severity, suggesting that home help did not meet the needs related to cognitive deterioration.
The interaction Cognitive ability × Age at the start of treatment exhibited a greater age difference and larger effect sizes (0.53 to 1.55) for patients with more cognitive severity.
Correlations between experimental task performance and general neuropsychological functions are summarized in Supplementary Table 2. Performance on experimental tests in the patient groups was significantly positively correlated with a standard measure of general cognitive severity (Mini-Mental State Examination score).
Finally, some biologically plausible interactions with cognitive severity at the start of treatment or with time in the study were included in the models, that is, gender, education, age, and functional ability at baseline.
The interaction effects of cognitive severity and age at baseline, time in months from the start of treatment, gender, and years of education showed that these variables cannot be interpreted separately.
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Cognitive impairment severity was assessed by the Hierarchic Dementia Scale (HDS) [ 34].
Finally, the number of previous episodes of depression of melancholic patients is predicted to positively correlate with cognitive deficits severity.
Cognitive impairment severity is the most significant predisposing factor for aggressive behaviour among older adults in long-term care facilities in the Quebec City area.
21 The self-regulation model includes emotional (fear, worry, and depression) and cognitive (timeline, severity, identity, cause, and cure/control) representation of illness.
Factors to consider in relation to advancing age that influence treatment decisions include co-morbidity, polypharmacy, visual and cognitive impairment, severity of vascular complications, psychosocial limitations, renal insufficiency, an increased risk of falling, and a limited life expectancy [ 1, 2].
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