Sentence examples for cognitive assay from inspiring English sources

Novel object recognition is used as an example of a cognitive assay which has been conducted successfully with a range of methods, all based on common principles of appropriate procedures, controls, and statistics.

To determine the utility of measuring the incremental benefit of spaced training as a cognitive assay that may be useful in early clinical trials, we used a within-subject crossover design, with two small samples (typical sample sizes for phase I clinical trials).

Cognitive effects were studied using the Alternating Lever Cyclic Ratio cognitive assay upon intraventricular injection with Aβ from various sources into rat brains and it was found that Aβ oligomers from all sources are potently able to induce cognitive defects.

We applied COMT Val158Met genotype to a familiar cognitive assay in order to re-examine the explanatory power of the tonic/phasic dopamine hypothesis for cognitive stability and flexibility, task characteristics that are inherent - and likely confounded - in many measures of working memory and executive function.

We (i) challenged participants by utilizing a cognitive assay that manipulated the level of required cognitive control within the same task, and (ii) examined whether Met carriers would display a performance advantage only when the cognitive control requirement was low, and Val carriers would perform better when the demand for cognitive control was increased.

Only by thoroughly modeling the cognitive assays being used can any data using these models be clearly and validly interpreted.

BACE1 knock out (KO) mice exhibited a range of Aβ lowering from 12% for heterozygous to >90% for homozygous animals, with cognitive benefits in multiple types of cognitive assays [ 14- 20].

Thus, because of the technical advantages, we tried to test the 'mGluR theory of FXS' by investigating the impact of a specific mGluR negative modulator, Fenobam, on the behavior of mice lacking FMRP ('fragile X mental retardation 1 knockouts' or ' Fmr1 KO mice') using the multifunctional, motor-cognitive assay on the Erasmus Ladder.

Mice were tested in the Y maze cognitive behavioral assay first.

Cognitive behavioral assays, histology, ELISA and Western blotting were used to assay the effect of J147 on memory, amyloid metabolism and neuroprotective pathways.

MP and RD carried out animal cognitive behavioral assays.