Accordingly, cerebellar volume changes were observed in patients with various mental disorders69,70,71, and that those with cerebellar damage had cognitive abnormalities in various domains72, 73.
Therefore, we have recently begun to use the term NC, which also reflects the depressive-like cognitive abnormalities present in this model37.
Results: Both disciplines had low rates of accurate detection of both cognitive abnormalities and symptoms of depression.
These experiments provide evidence that Tat protein expression is sufficient to mediate cognitive abnormalities seen in HIV-infected individuals.
Describe initial development and validation of a test battery composed of established instruments designed to detect, via telephone interview, cognitive abnormalities in survivors of acute respiratory distress syndrome.
We investigated cognitive abnormalities using standard tests in Chinese patients with idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD) compared with those in normal controls.
Prominent cognitive abnormalities, especially in memory functioning, have motivated research designed to elucidate the mediating mechanisms that produce PTSD symptoms, especially those involving involuntary recollection.
Professor McNally's main research emphasis has concerned the psychopathology of anxiety and related disorders (e.g., panic disorder, specific phobia, obsessive-compulsive disorder [OCD], social anxiety disorder, and posttraumatic stress disorder), especially the cognitive abnormalities constitutive of these syndromes.
"It's not because we want to implant or 'incept' some false experience into the human mind, but because it could be useful, eventually, to develop methods to reduce cognitive abnormalities associated with psychiatric diseases, such as the delusions experienced by patients with schizophrenia," says Tonegawa.
Our findings further indicate that Gtf2i haploinsufficiency plays an important role in the neurodevelopmental and cognitive abnormalities of WBS and that it is possible to rescue part of this neurocognitive phenotype by restoring Gtf2i expression levels in specific brain areas.
Although results from neuropsychological and neuroimaging studies have postulated the involvement of the frontal lobe and the subcortical brain regions in the pathophysiology of obsessive compulsive disorder (OCD), neuroimaging studies have provided little evidence that cognitive abnormalities in patients with OCD are related to dysfunctions in these areas.
