Several simplified membrane models featuring coexisting liquid disordered (Ld) and ordered (Lo) lipid phases have been developed to mimic the heterogeneous organization of cellular membranes, and thus, aid our understanding of the nature and functional role of ordered lipid protein nanodomains, termed "rafts".
Given the diversity of coexisting and complementary explanatory models, various predictions may be made.
Due to nonlinearity, these dynamic models exhibit coexisting attractors, nonuniformity of phase portraits, and high sensitivity of boundaries of basins of attraction.
The sp2 phase in amorphous carbon is modeled as coexisting nc-graphite, fused aromatic ring, and olefinic chain clusters.
Our findings accommodate the prevailing BAK activation models as potentially coexisting mechanisms capable of initiating BAK activation, and supports a model based approach for predicting resistance to therapeutically relevant small molecule BH3 mimetics.
The Vfold model predicts two coexisting structure (I, II), corresponding to the extended-duplex and kissing-loop dimers; respectively.
The situation of bi-stability and the existence of two coexisting equilibria for the proposed model system are addressed.
Therefore, nodal interpolations are required for both the scaffold and cross-linking solid constituents, thereby modeling concurrent and coexisting constituents.
After explaining how to properly estimate this quantity, it is shown how to correctly perform the double-tangent construction of coexisting phases for binary systems modeled with the gamma-phi approach.
Moreover, forcing the term for total coexisting conditions into the multivariable model expressly to control for confounding did not change the results for any of the significant terms.
We tested for stoichiometric asymmetry by selecting a null model that assumes that coexisting repeat arrangements (i.e., those that coexist in the same master or subgenomic circular chromosome) should be present at equal frequencies.
