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Consider (1) Dose Rat mg / Kg = Dose Mouse (mg / Kg ) × Coefficient Rat Coefficient Mouse × Body weight Rat Body weight Mouse 2 / 3. Serum creatinine (SCr) levels were determined by high-performance liquid chromatography (HPLC) as described previously [ 25].
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The apparent permeability coefficient across rat jejunum of enalaprilat entrapped in PLGA nanoparticles is not significantly improved compared with enalaprilat in solution.
In this paper, the transmission loss (TL) and absorption coefficient of rat and porcine skins were measured, and the synthesized skin was then implemented by using a gelatin gel that is widely used as an ultrasound phantom.
We applied the extended RICS protocol to determine diffusion coefficients in rat cardiomyocytes.
The experiments were designed into two main parts: (1) in vivo experiments on body temperature of conscious rats; (2) in vitro experiments on temperature sensitivity (temperature coefficient, TC) of rat PO/AH neurons in slice preparations.
Intestinal absorption flux coefficient in everted rat intestine (kU) were measured with reference solutions (RS) of free AMFQ (kURS II>kURS I) and with hydrogels (H), in which the pattern was reversed since kUH I>kUH II.
Body weight, AGD, organ weight, and organ coefficient of each rat on PND90 are shown in Figure 1.
In the present study, our aim was to find out if tezosentan reverses the rise in microvascular filtration coefficient (Kfc) in rat lungs that have been isolated and perfused 12 h after cecum ligation and puncture (CLP) or infusion of ET-1.
Further, the absorption coefficients or the rat and porcine skin were measured as 0.029 ± 0.011 and 0.031 ± 0.012 at 1 kHz, respectively.
Thus our analysis gives overall reduction of diffusion coefficients in the rat cardiomyocytes.
Intra-assay reproducibility is indicated by the following coefficients of variation: at rat TNF-α mass 1,024.4 pg/ml the coefficient was 6.6, and at rat TNF-α mass of 376.5 pg/ml it was 3.7.
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